Brooks Womens Glycerin GTS 22 Supportive Running Shoe (Style 93C6)

In this review the Brooks Womens Glycerin GTS 22 stands out as a cushioned, supportive road running shoe built for women who want plush landings with guided stability. The single biggest reason to buy is the combination of Brooks DNA Tuned cushioning and GuideRails support, which together deliver soft heel impact and controlled toe-offs while keeping excess motion in check, making them especially useful for runners or gym users who need extra support without a heavy, restrictive feel.

Key Features

• GuideRails support: Keeps excess motion at bay to stabilize the foot and reduce strain during runs or cross training.
• DNA Tuned cushion: Larger midsole cells in the heel and smaller cells in the forefoot give plush landings with responsive toe-offs for smoother transitions.
• Accommodating fit: The double jacquard knit upper flexes with the foot to offer breathability and a comfortable, adaptive fit.
• Smooth, stable transitions: A broad platform and tuned heel-to-toe geometry help the foot roll forward with consistent stability.
• Diabetic shoe certified: Certified PDAC A5500, which signals an accommodating internal volume and care for users with specific foot health needs.

Who It's For

This shoe is best for road runners and active women who prioritize cushioning plus support, including those recovering from foot pain or who appreciate extra arch control during long runs, gym sessions, or daily walking. The GuideRails system benefits runners with mild overpronation or anyone who wants to limit excess motion without a rigid corrective feel.

Shoppers who prefer an extremely narrow racing fit or want a minimalist, low-drop trainer may want to look elsewhere; a few customers report mixed impressions of toe box width and cushioning firmness, so those needing a very wide toe box or a different ride feel should try these on first.

Pros & Cons

Pros

• Exceptional cushioning and soft heel landings thanks to DNA Tuned midsole technology.
• GuideRails system provides noticeable stability and reduced unwanted motion.
• Comfortable, breathable double jacquard knit upper that adapts to the foot.
• Certified PDAC A5500 diabetic shoe, offering an accommodating interior for special foot care.

Cons

• Fit and toe box width are mixed among customers, so sizing may require trying a pair to confirm comfort.
• Some runners disagree on cushioning level; preferences for a firmer or softer ride vary.

Specifications

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for women who want plush cushioning paired with guided stability; its DNA Tuned midsole and GuideRails make it especially suited to road runners and active users who need controlled motion and comfort. Given the support features and diabetic certification, it offers solid value for anyone seeking a stable, comfortable daily trainer, but try the fit first if you have very wide toes or a strict preference for ride firmness.

Frequently Asked Questions

Are these shoes good for overpronation?
The GuideRails support system helps control excess motion and is suitable for mild to moderate overpronation.

Do they have a roomy toe box?
Customer feedback is mixed; some find ample toe room while others feel the toe box is narrow, so trying them on is recommended.

Can I use them for the gym and road running?
Yes, they are designed for road running and cross training and perform well for gym workouts and everyday wear.