Brooks Womens Glycerin GTS 22 Supportive Running Shoe (Style GXZV)

In this review the Brooks Womens Glycerin GTS 22 emerges as a cushioned, supportive road running shoe best suited to runners and walkers who need stability without sacrificing plush comfort. The single biggest reason to consider these shoes is the combination of Brooks DNA Tuned cushioning with the GuideRails support system, which together create remarkably smooth heel-to-toe transitions while keeping excess motion under control. Reviewers consistently note immediate comfort and relief from foot pain, making the Glycerin GTS 22 a practical choice for everyday mileage and recovery runs.

Key Features

• GuideRails support: The holistic GuideRails system keeps excess motion in check so the foot follows a natural path and provides extra stability during longer runs.
• DNA Tuned cushion: Dual-size midsole cells offer larger heel cells for soft landings and smaller forefoot cells for responsive toe-offs, improving transition feel.
• Accommodating fit: The double jacquard knit upper stretches where needed and breathes well, creating a comfortable fit for varied foot shapes.
• Stable platform: A broad base and tuned heel/forefoot deliver smooth, stable transitions from heel strike to push-off on road surfaces.
• Certified diabetic option: The shoe is PDAC A5500 certified, making it a viable choice for customers needing diabetic shoe features.

Who It's For

The Glycerin GTS 22 is best for recreational and dedicated road runners who want plush cushioning plus guidance to limit excess motion, and for people seeking relief from foot, hip, or back discomfort through better support. It also works well as an everyday training shoe, for gym sessions, and for anyone who values a soft landing with a springier toe-off.

Runners who prefer an ultra-wide, minimalist or zero-drop shoe should look elsewhere, and those who need a very narrow toe box may find mixed results on fit; customer feedback shows toe space can feel roomy for some and snug for others, so trying on a pair is advisable.

Pros & Cons

Pros

• Excellent combined cushioning and stability from DNA Tuned and GuideRails for smoother transitions.
• Comfortable, breathable double jacquard knit upper that accommodates varied foot shapes.
• Relief of foot pain reported by customers, with improved comfort during daily wear and runs.
• PDAC A5500 certification makes it suitable for users needing diabetic-friendly footwear.

Cons

• Fit and sizing receive mixed feedback; the toe box may feel too narrow for some users.
• Cushioning feel divides opinion-some find it plush while others prefer firmer responsiveness.

Specifications

Brand	Brooks
Model	Glycerin GTS 22
Support	GuideRails holistic support system
Midsole	DNA Tuned dual-size cell cushioning
Upper	Double jacquard knit, breathable and accommodating
Use	Road running, cross training, gym, everyday wear
Certification	PDAC A5500 diabetic shoe

Our Verdict

The Brooks Glycerin GTS 22 is a strong choice for runners and walkers who want plush cushioning paired with dependable support for natural movement control. It represents good value for those who prioritize comfort, stability, and diabetic-friendly certification, though shoppers sensitive to toe box width should try them on before committing.

Frequently Asked Questions

Are these shoes good for people with foot pain?
Yes, many customers report reduced foot, hip, and back discomfort thanks to the combination of cushioning and GuideRails support.

How does the fit run?
Fit is mixed in user reports; some experience a roomy toe area while others find the toe box narrower, so trying a size is recommended.

Can I use these for gym workouts as well as running?
Yes, the Glycerin GTS 22 is suitable for road running, cross training, and gym sessions due to its stable platform and cushioning.