Brooks Womens Glycerin GTS 22 Supportive Running Shoe (Style JGBG)

Our review of the Brooks Womens Glycerin GTS 22 finds it best for runners and gym-goers who prioritize plush cushioning combined with built-in stability. The single biggest reason to pick these shoes is the blend of DNA Tuned cushioning and the GuideRails support, which together deliver soft landings and controlled motion throughout long road runs or daily training sessions. They are a clear evolution from the previous model with an accommodating knit upper and a broad platform that promotes smooth heel-to-toe transitions.

Key Features

• GuideRails support: Helps keep excess motion in check so the foot and knees track more naturally during runs and cross training.
• DNA Tuned cushion: Larger heel cells and smaller forefoot cells provide plush landings with responsive toe-offs for a balanced ride.
• Accommodating fit: Double jacquard knit upper stretches in key areas to combine breathability with a secure hold across the midfoot.
• Smooth, stable transitions: A broad platform and tuned heel/forefoot geometry reduce abrupt shifts for a more confident stride.
• Certified diabetic option: The shoe is PDAC A5500 certified, making it suitable for customers needing diabetic-friendly footwear.

Who It's For

The Glycerin GTS 22 suits recreational and dedicated road runners who want maximum cushioning without sacrificing stability, and athletes who cross between running and gym work where a stable base helps. Its plush midsole and GuideRails are also welcome for walkers and anyone who benefits from controlled pronation support.

Runners who need a very wide toe box or those who prefer minimalist, low-stack trainers should look elsewhere, as some users report a narrower toe feel. If you want a lighter racing flat, this maximal-cushion supportive shoe is not the ideal choice.

Pros & Cons

Pros

• Luxurious cushioning with a responsive toe-off thanks to DNA Tuned midsole design.
• Reliable GuideRails support reduces excess movement for a more stable run.
• Comfortable, breathable double jacquard knit upper that adapts to foot shape.

Cons

• Some customers find the toe box a bit narrow, so fit can vary and trying on is recommended.

Specifications

Model	Glycerin GTS 22
Support system	GuideRails holistic support
Cushioning tech	DNA Tuned midsole (dual-size cells)
Upper	Double jacquard knit, breathable and flexible
Best for	Road running, cross training, gym use, walking
Diabetic certified	PDAC A5500 certified

Our Verdict

The Brooks Glycerin GTS 22 is a strong pick for runners who want plush cushioning paired with thoughtful stability features; it delivers comfortable rides on long road runs and supports varied training. Given its materials and PDAC certification, it represents solid value for buyers who prioritize comfort and joint-friendly support over a minimalist feel.

Frequently Asked Questions

Are these shoes good for long runs?
Yes, the DNA Tuned cushioning and broad platform make the Glycerin GTS 22 comfortable for longer road runs.

Do they provide motion control for overpronation?
The GuideRails support helps keep excess motion in check and is aimed at stabilizing natural movement rather than rigid correction.

Do they run true to size?
Fit varies: many find the upper accommodating, but some users report a narrower toe box, so trying on is recommended.