Brooks Womens Glycerin GTS 22 Supportive Running Shoe (Style M9LC)

Our review of the Brooks Womens Glycerin GTS 22 finds it best for runners and active women who want plush cushioning paired with firm guidance. The single biggest reason to buy is the combination of the updated DNA Tuned midsole and GuideRails support, which together deliver a soft landing and a controlled, stable toe-off that reduces excess motion and helps relieve foot, hip and back discomfort.

Key Features

• GuideRails support: Keeps excess movement in check so the foot and adjacent joints move along a natural path, improving stability during runs and workouts.
• DNA Tuned cushion: Larger heel cells create a soft, plush landing while smaller forefoot cells deliver responsive toe-offs for energetic transitions.
• Accommodating fit: The double jacquard knit upper stretches where needed and breathes well while remaining durable for regular road use.
• Smooth transitions: A broad platform with a tuned heel and forefoot smooths heel-to-toe motion for more confident strides.
• Certified diabetic fit: The Glycerin GTS 22 is PDAC A5500 certified, making it suitable for runners who need a diabetic shoe option.

Who It's For

This shoe suits women who log miles on the road, use the gym for cross training, or need everyday support with a cushioned, stable ride. Runners who favor plush cushioning but appreciate guidance to limit excess motion will find the Glycerin GTS 22 a balanced option.

Shoppers who prefer an extremely narrow toe box or those seeking a minimalist, low-drop trainer should look elsewhere; the Glycerin GTS 22 emphasizes cushioning and stability over a minimalist feel.

Pros & Cons

Pros

• Excellent cushioning and soft landings from the DNA Tuned midsole.
• Effective stabilization from GuideRails to reduce excess motion and related discomfort.
• Comfortable, breathable upper that accommodates varied foot shapes for many wearers.

Cons

• Fit can be inconsistent for some users, with reports of a toe box that feels narrow for certain foot shapes.

Specifications

Our Verdict

The Brooks Womens Glycerin GTS 22 is a strong choice for women who want plush cushioning with built-in stabilization. It offers good value for runners and active users who need support and comfort that can help ease foot and related joint pain, while shoppers needing a very narrow racer or minimalist shoe should consider alternatives.

Frequently Asked Questions

Are these shoes good for long road runs?
Yes - the DNA Tuned cushion and broad platform create comfortable landings and stable transitions for longer road sessions.

Do they run true to size?
Fit is mixed; many find the upper accommodating but some users report the toe box feels narrow, so try them on if possible.

Can people with diabetic foot concerns use them?
Yes - the Glycerin GTS 22 is PDAC A5500 certified for diabetic shoe use.