Brooks Womens Glycerin GTS 22 Supportive Running Shoe (Style RHS9)

In this review of the Brooks Womens Glycerin GTS 22, the bottom line is simple: this shoe is for women who want luxurious cushioning with added stabilization. The Glycerin GTS 22 pairs Brooks' latest DNA Tuned Cushion midsole with the GuideRails support system to deliver plush landings and managed motion for road running, gym sessions, or everyday wear. Reviewers note immediate comfort, reduced foot pain and improved alignment, making this model a strong choice for runners who value both softness and support.

Key Features

• GuideRails support: Keeps excess movement in check so the foot and knee track more naturally during runs and cross training.
• DNA Tuned cushion: Larger heel cells create soft landings while smaller forefoot cells provide responsive toe-offs for smoother transitions.
• Accommodating knit upper: Double jacquard knit offers breathability and a flexible fit that adapts to the foot without feeling restrictive.
• Broad platform: Stabilizes the foot through heel-to-toe movement for a secure, confidence-inspiring stride.
• Certified diabetic-friendly: The Glycerin GTS 22 is PDAC A5500 certified, indicating suitability for many users with foot health concerns.

Who It's For

The Glycerin GTS 22 suits women who prioritize plush cushioning combined with structured support, particularly runners who experience mild pronation or who want extra stabilization for longer road runs and daily training. It also works well for gym workouts and anyone seeking a cushioned shoe that eases foot, hip, or back discomfort.

Runners who prefer a very narrow toe box or those seeking an ultra-minimal, zero-drop shoe should look elsewhere; customers reported mixed feedback on toe box width and subjective cushioning levels, so those with very specific fit preferences may want to try them on first.

Pros & Cons

Pros

• Exceptional, plush cushioning that reduces impact and can relieve foot pain.
• GuideRails system provides noticeable stabilization without feeling intrusive.
• Breathable, flexible knit upper that adapts to the foot for daily comfort.
• Certified PDAC A5500 diabetic-friendly construction for added foot health assurance.

Cons

• Fit is mixed among users; some find the toe box roomy while others find it too narrow, so sizing may require trying on.
• Perceptions of cushioning differ by runner, so those preferring firmer rides may not agree with the plush feel.

Specifications

Model	Glycerin GTS 22
Support System	GuideRails holistic support
Cushioning	DNA Tuned midsole with dual-size cells
Upper	Double jacquard knit, flexible and breathable
Use	Road running, cross training, gym
Diabetic Certification	PDAC A5500 certified
Predecessor	Glycerin GTS 21

Our Verdict

The Brooks Womens Glycerin GTS 22 is an excellent option for women who want luxurious cushioning plus reliable support. It is good value for runners looking to reduce impact and stabilize motion without sacrificing comfort, though prospective buyers should confirm fit due to mixed feedback on toe box width and personal cushioning preference.

Frequently Asked Questions

Are these shoes good for mild pronation?
Yes, the GuideRails system is designed to control excess motion and helps runners with mild pronation maintain a more natural gait.

Do they run narrow or wide?
Fit is mixed: some customers report a roomy toe area while others find the toe box narrow, so trying on or checking return options is recommended.

Can these be used for gym workouts?
Yes, the combination of cushioning and stability makes them suitable for road running and cross training, including most gym activities.