Glycerin 22 Men's Neutral Running Shoe - Max Cushioning

Our review of the Glycerin 22 Men's Neutral Running Shoe finds it best suited to runners and walkers who want maximum cushioning without extra stability features. The single biggest reason to consider these is the updated DNA Tuned cushion, which blends larger heel cells for soft landings with smaller forefoot cells for responsive toe-offs, producing notably smooth transitions from heel to toe on road runs and long walks. The shoe's certification as a PDAC A5500 diabetic shoe and the APMA Seal of Acceptance underline its comfortable, foot-friendly design.

Key Features

• Neutral support: Offers neutral support while delivering the maximum amount of cushioning, making it versatile for road running, cross training, and daily wear.
• DNA Tuned cushion: Larger heel cells create plush landings and smaller forefoot cells promote energetic toe-offs for balanced ride quality.
• Accommodating fit: The double jacquard knit upper provides flexibility and breathability, adapting well to different foot shapes.
• Smooth transitions: A broad platform and tuned heel and forefoot work together to stabilize the foot and smooth heel-to-toe movement.
• Medical endorsements: Certified PDAC A5500 diabetic shoe with the APMA Seal of Acceptance, supporting foot health for sensitive users.

Who It's For

The Glycerin 22 is aimed at men who prioritize cushioning and comfort over corrective support, including road runners, walkers, and gym-goers who appreciate plush underfoot feel during longer sessions. Its stable broad platform and cushioning make it a good pick for everyday wear and for people with foot sensitivity who value certified designs.

Those who need firm medial support or corrective guidance should look elsewhere, for example at models explicitly billed as stability or guidance shoes. Also, potential buyers with very narrow feet should try them on first, since customer feedback varies on fit.

Pros & Cons

Pros

• Exceptionally comfortable cushioning that reduces impact on runs and walks.
• Accommodating knit upper balances breathability with a flexible fit.
• Medical certifications add confidence for users with sensitive feet.

Cons

• Fit varies among users; some find the width narrow while others find it wide, so sizing trials are advisable.

Specifications

Brand	Brooks
Model	Glycerin 22 (men's neutral)
Support type	Neutral
Cushion technology	DNA Tuned midsole with dual-size cells
Upper	Double jacquard knit, breathable and flexible
Certifications	PDAC A5500 diabetic shoe, APMA Seal of Acceptance

Our Verdict

The Glycerin 22 is a strong choice for runners and everyday walkers who want the maximum plush cushioning and smooth transitions without added stability features. Given its comfortable ride, accommodating upper, and medical endorsements, it represents good value for anyone prioritizing cushioning and foot health, though shoppers should confirm fit before buying.

Frequently Asked Questions

Are these shoes good for long runs?
Yes; the DNA Tuned cushion and broad platform provide plush impact protection and stable transitions for longer road runs.

Do they suit wide feet?
Customer reports vary-some find them comfortable for wide feet while others find them narrow; try before you commit if you have a very wide foot.

Are these appropriate for people with foot sensitivity?
Yes, the PDAC A5500 certification and APMA Seal indicate they are designed with foot health and comfort in mind.