Glycerin 22 Mens Neutral Running Shoe - Maximum Cushioned Ride

In this review of the Glycerin 22 Mens Neutral Running Shoe the bottom line is simple: this is a plush, highly cushioned road running shoe for men who prioritize comfort and smooth transitions. The standout reason to buy is the updated DNA Tuned cushion, which blends dual-size midsole cells to deliver soft heel landings and responsive toe-offs while preserving a broad, stable platform. Reviewers praise the shoe for exceptional heel cushioning and an accommodating fit that works well for walking, running and wider feet.

Key Features

• DNA Tuned Cushion: Larger heel cells provide soft, plush landings while smaller forefoot cells create a more energetic toe-off for smoother gait transitions.
• Neutral Support: Designed as a neutral shoe, it offers the maximum amount of cushioning without corrective motion control for runners who do not need extra pronation support.
• Accommodating Fit: The double jacquard knit upper stretches to fit wider feet comfortably while maintaining breathability and durability.
• Stable Platform: A broad sole stabilizes the foot through heel-to-toe transitions, helping runners feel steady on road surfaces.
• Certified Diabetic and APMA Accepted: The Glycerin 22 is PDAC A5500 certified and carries the APMA Seal of Acceptance, supporting foot health needs.

Who It's For

The Glycerin 22 is best for male runners and walkers seeking maximum cushioning on road runs, treadmill miles, or long walks, and for people with wider feet who need an accommodating upper. It also appeals to those with flat feet who want supportive cushioning rather than motion control.

Runners who need firm stability, aggressive pronation control, or a minimalist, low-drop trainer should look elsewhere; for added support consider a Glycerin GTS model. Also, budget shoppers should note some buyers consider these shoes pricier than basic trainers.

Pros & Cons

Pros

• Excellent cushioned feel, especially at the heel, for comfortable long miles and walking.
• Accommodating knit upper provides a roomy fit that suits wide feet without binding.
• Smoothed transitions from heel to toe thanks to tuned midsole cell design and a broad platform.

Cons

• Some buyers report mixed feedback on sizing, so fit can be inconsistent between feet or compared to other brands.
• Perceived value varies, with a few customers feeling the price is high for a cushioning-focused trainer.

Specifications

Our Verdict

The Glycerin 22 is a strong choice for men who want plush cushioning and a roomy, breathable fit for road running, gym sessions, or daily walking. Its DNA Tuned midsole and stable platform create smooth transitions and supportive cushioning, making it worth the investment for comfort-focused runners, though shoppers should check sizing carefully before buying.

Frequently Asked Questions

Are these shoes good for wide feet?
The double jacquard knit upper is designed to be flexible and accommodating, making the Glycerin 22 comfortable for many people with wider feet.

Do these provide arch support for flat feet?
They are a neutral shoe with generous cushioning; many customers with flat feet reported good comfort and support, but those needing strong corrective support should consider a stability model.

Do they run true to size?
Customer feedback is mixed on sizing, so it is recommended to try them on or follow the retailer size guidance before purchasing.