Glycerin GTS 22 for Men - Plush Cushioning with Support

Our review of the Glycerin GTS 22 for men finds it best suited to runners and walkers who prioritize plush cushioning plus a touch of stability. The single biggest reason to buy is the DNA Tuned midsole, which blends larger heel cells with smaller forefoot cells to deliver soft landings and responsive toe-offs while keeping transitions smooth. Certified as a PDAC A5500 diabetic shoe and bearing the APMA Seal of Acceptance, this iteration adds accommodating upper materials and a broader platform for reliable day-to-day comfort and support.

Key Features

• DNA Tuned Cushion: Larger heel cells provide soft, plush landings while smaller forefoot cells encourage energetic toe-offs for a balanced ride.
• Neutral Support with Added Stability: The shoe offers neutral support and a broad platform that stabilizes the foot for smoother heel-to-toe transitions.
• Accommodating Fit: The double jacquard knit upper flexes with the foot and improves breathability while remaining durable.
• Certified Medical and Professional Acceptance: Built as a PDAC A5500 diabetic shoe and granted the APMA Seal of Acceptance for foot health considerations.
• Versatile Use: Designed for road running, cross training, gym workouts, and extended walking where maximum cushioning is desired.

Who It's For

The Glycerin GTS 22 is ideal for men who want maximum cushioning without sacrificing a stable platform, including everyday road runners and walkers, people with flat feet seeking supportive cushioning, and those who value a more protective heel. Its certified diabetic shoe status also makes it a sensible choice for customers needing foot-friendly footwear.

Runners who want a minimal, race-day speed shoe should look elsewhere; the Glycerin GTS 22 leans toward comfort and plush transitions rather than lightweight performance. Also, shoppers who require an extra roomy or very narrow toe box should try the shoe on first, as sizing feedback varies among users.

Pros & Cons

Pros

• Exceptionally comfortable cushioning that supports long walks and runs.
• Broad platform and tuned midsole deliver smooth, stable transitions.
• Accommodating knit upper provides breathability and a flexible fit.
• Medical-friendly certifications add confidence for sensitive feet.

Cons

• Some users report variation in fit, with a few finding the toe box slightly narrow or running small.
• Not designed for racers who prioritize minimal weight or maximal ground feel.

Specifications

Model	Glycerin GTS 22
Intended use	Road running, walking, cross training
Support	Neutral support with stabilizing platform
Midsole technology	DNA Tuned with dual-size midsole cells
Upper	Double jacquard knit, flexible and breathable
Medical seals	PDAC A5500 diabetic shoe; APMA Seal of Acceptance

Our Verdict

The Glycerin GTS 22 for men is a strong pick for anyone who values maximum cushioning paired with stability and foot-health credentials; it provides excellent day-to-day comfort for walkers and road runners and represents good value for shoppers prioritizing protective, plush running shoes.

Frequently Asked Questions

Are these shoes good for flat feet?
Yes. Customers report the Glycerin GTS 22 offers good support and cushioning that benefits flat feet thanks to the broad platform and tuned midsole.

Do these run true to size?
Fit feedback is mixed; many find them true to size and accommodating, but some report they run small or have a narrower toe box, so trying them on is recommended.

Can I use these for gym workouts?
Yes. They work well for road running, cross training, and general gym use where cushioning and smooth transitions are desired.