Natural Factors RxOmega-3 Fish Oil 1260 mg per Serving - Heart Support
Natural Factors RxOmega-3 Fish Oil 1260 mg per Serving - Heart Support
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Our review of Natural Factors RxOmega-3 finds it best suited to anyone seeking a high-strength, pharmaceutical-grade fish oil without the usual aftertaste. The bottom line: this 240-count bottle delivers a concentrated 1260 mg omega-3 dose per serving with a balanced 800 mg EPA and 400 mg DHA profile, and the Enteripure softgels mean users report no fishy aftertaste or stomach upset. For people focused on heart health and clear purity standards, this product stands out as an effective, easy-to-swallow daily supplement.
Key Features
- Pharmaceutical grade: Molecularly distilled and ultra-purified oil comes from clean sources to reduce environmental contaminants.
- Balanced EPA and DHA: The 800 mg EPA and 400 mg DHA split provides targeted support for cardiovascular and cognitive function.
- High potency: At 1260 mg omega-3 per serving, it delivers an effective dose for those looking to support circulation and cholesterol management.
- Enteripure delivery: Softgel technology embeds ingredients in the casing to prevent breakdown in the stomach and reduce fishy aftertaste.
- Third-party tested: Independent testing verifies purity and safety from PCBs and mercury, meeting strict international quality standards.
- No fishy aftertaste: Many users note no lingering taste or reflux, improving daily adherence.
Who It's For
This product is well suited to adults who want a high-strength omega-3 supplement with pharmaceutical-grade purity and a specific EPA/DHA ratio aimed at heart and circulation support. It is a practical choice for those who have had issues with fishy aftertaste from other brands because the Enteripure softgels and formulation minimize flavor and reflux.
People who need precise medical dosing or supervised prescription therapy should consult a clinician first; also, those seeking plant-based omega-3 sources should look elsewhere. If capsule size or swallowing difficulty is a major concern, check softgel dimensions before purchasing.
Pros & Cons
Pros
- Pharmaceutical-grade purification reduces risk of contaminants, reflecting high purity.
- High EPA and DHA totals provide meaningful support for heart, mood, and joint comfort.
- Enteripure softgels eliminate the common fishy aftertaste and improve swallowability for many users.
- Third-party testing and strict quality standards increase consumer confidence in safety.
Cons
- Large bottle count may be unnecessary for occasional users and could be more than needed for short-term trials.
- Not suitable for those seeking a vegetarian or algal omega-3 source.
Specifications
| Product type | Pharmaceutical-grade fish oil supplement |
| Omega-3 per serving | 1260 mg |
| EPA | 800 mg per serving |
| DHA | 400 mg per serving |
| Count | 240 softgels |
| Delivery technology | Enteripure softgels |
| Testing | Third-party tested for PCBs and mercury |
Our Verdict
Natural Factors RxOmega-3 is a strong value for anyone wanting a concentrated, pharmaceutical-grade omega-3 with an effective EPA/DHA balance and minimal aftertaste. It is particularly good for people prioritizing heart health and product purity, though those needing plant-based omega-3s or very small trial sizes may prefer alternatives.
Frequently Asked Questions
Will these softgels cause a fishy aftertaste?
Most users report no fishy aftertaste due to the Enteripure softgel technology that prevents stomach breakdown and reflux.
Are these tested for heavy metals?
Yes, the product is third-party tested to ensure purity and safety from PCBs and mercury.
What is the EPA to DHA ratio?
The formula provides 800 mg EPA and 400 mg DHA per serving for a 2:1 EPA to DHA balance.
Editor's Take
Natural Factors RxOmega-3 delivers a high-strength, pharmaceutical-grade 1260 mg omega-3 dose with 800 mg EPA and 400 mg DHA, offering strong heart and circulation support with minimal aftertaste and verified purity.

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