Women's Adrenaline GTS 22 Supportive Running Shoe - Pink/Blackened

Our review of the Women's Adrenaline GTS 22 finds a supportive, well-cushioned running shoe that suits runners who want stability without harsh correction. The biggest reason to consider these shoes is the combination of Brooks' GuideRails holistic support and a fully updated DNA LOFT midsole that gives a softer, smoother ride from landing to toe-off; this makes them a strong choice for road runners and gym users who need help with overpronation but do not want a heavy, bulky feel.

Key Features

• GuideRails support: The holistic GuideRails system keeps excess knee and foot movement in check so runs feel more controlled and less fatiguing.
• 100% DNA LOFT cushioning: The updated midsole delivers a softer, more energetic ride with smoother transitions through the Segmented Crash Pad.
• APMA Seal and diabetic-friendly: Certified by PDAC A5500 and accepted by the APMA, indicating suitability for users needing therapeutic, supportive footwear.
• Modernized fit: 3D Fit Print upper technology provides structure and a secure fit without adding unnecessary bulk.
• Versatile use: Designed for road running, cross training and everyday wear, offering stable support whether on pavement or at the gym.

Who It's For

These shoes are best for women runners who overpronate and want substantial yet comfortable support rather than rigid motion control. They also suit people seeking a soft, cushioned ride for medium to long distances on roads or for cross training sessions.

Runners who prefer minimal or zero-support shoes, or those who need a very narrow fit, should look elsewhere; the Adrenaline GTS 22 favors a roomier toe box and stable construction that some users may find too structured for barefoot-style running.

Pros & Cons

Pros

• Comfortable, soft cushioning that smooths transitions during the gait cycle.
• Effective GuideRails support that reduces excess knee movement and stabilizes overpronation.
• Quality construction and a modernized, less bulky fit thanks to targeted 3D Fit Print engineering.
• Certified PDAC A5500 and APMA accepted for diabetic and therapeutic use.

Cons

• Some buyers report inconsistent durability, with a minority experiencing early wear.
• Runners who prefer a very minimal shoe may find the support and cushioning too substantial.

Specifications

Model	Adrenaline GTS 22
Gender	Women
Color	Pink/Blackened Pearl
Cushioning	100% DNA LOFT with Segmented Crash Pad
Support System	GuideRails holistic support
Certifications	PDAC A5500 Diabetic shoe, APMA Seal of Acceptance
Predecessor	Adrenaline GTS 21

Our Verdict

The Adrenaline GTS 22 is a smart pick for women who need reliable support for overpronation combined with plush cushioning. It offers strong value for road runners and gym users who want a stable, comfortable shoe that reduces excess knee motion while delivering a smooth ride.

Frequently Asked Questions

Are these shoes good for overpronation?
Yes, the GuideRails system is designed to control excess movement and support runners who overpronate.

Do they run true to size?
Brooks recommends ordering about 1/2 to one full size larger than your dress shoe for the best fit.

Are they suitable for diabetic feet?
Yes, this model is PDAC A5500 certified and carries the APMA Seal of Acceptance for therapeutic suitability.