Womens Glycerin 22 Neutral Running Shoe - Plush Neutral Cushioning

In this review the Brooks Womens Glycerin 22 Neutral Running Shoe stands out as a top pick for runners and everyday athletes who want maximum cushioning without extra medial support. The bottom line: this shoe is for women seeking a soft, stable ride for road running, gym sessions, and long walks, with the added assurance of PDAC A5500 diabetic certification and the APMA Seal of Acceptance. The review finds the Glycerin 22 delivers a luxe, responsive feel thanks to Brooks DNA Tuned midsole design and a roomy, accommodating knit upper that keeps toes comfortable during extended wear.

Key Features

• DNA Tuned Cushion: Larger heel cells and smaller forefoot cells combine to give plush landings and energetic toe-offs for a smooth stride.
• Neutral Support: Provides a neutral platform that maximizes cushioning without adding corrective support, making it versatile for many activities.
• Accommodating Fit: The double jacquard knit upper stretches to fit a range of foot shapes while remaining breathable and durable.
• Stable Transitions: A broad platform and tuned heel/forefoot promote stable, smooth heel-to-toe transitions over road surfaces.
• Medical Certifications: Certified PDAC A5500 for diabetic use and carries the APMA Seal of Acceptance, useful for shoppers prioritizing foot health.

Who It's For

The Glycerin 22 is best for women who value maximum cushioning and a soft ride: long-distance road runners who want plush shock absorption, gym-goers who need comfortable trainers for cross training, and walkers who appreciate roomy toe boxes and padded heels. Its neutral support suits those without significant overpronation who prefer a responsive yet forgiving midsole.

Runners seeking strong corrective or stability features should look at Glycerin GTS models or other stability lines, since this neutral version focuses on cushioning rather than motion control. Also, minimalists or racers looking for a lightweight, highly responsive race shoe may find the Glycerin 22 feels heavier due to its emphasis on plush cushioning.

Pros & Cons

Pros

• Exceptional cushioning from DNA Tuned delivers comfortable landings and lively toe-offs.
• Roomy, breathable engineered knit upper provides a comfortable fit for wider toes and longer runs.
• Certified PDAC A5500 and APMA acceptance give confidence for users concerned about foot health.

Cons

• As a maximum-cushion neutral shoe, it may feel bulky to runners wanting a lightweight race shoe.
• Some buyers note price sensitivity; perceived value varies among customers.

Specifications

Model	Glycerin 22
Gender	Womens
Support Type	Neutral
Midsole Technology	DNA Tuned with dual-size cells
Upper	Double jacquard knit, breathable
Certifications	PDAC A5500 diabetic shoe; APMA Seal of Acceptance

Our Verdict

The Brooks Womens Glycerin 22 is a solid choice for women who prioritize cushioning and comfort over aggressive stability or minimal weight. With DNA Tuned cushioning, a forgiving knit upper, and medical certifications, it suits road runners, walkers, and gym users who want plush support and a reliable, smooth ride at everyday training paces.

Frequently Asked Questions

Are these shoes good for long road runs?
Yes, the plush midsole and stable platform make them well suited to long road runs where cushioning and smooth transitions matter.

Do they provide arch support for overpronation?
No, this is a neutral shoe; runners needing extra arch support should consider a stability variant like Glycerin GTS models.

Are they suitable for people with diabetes?
Yes, the Glycerin 22 is certified PDAC A5500 and has the APMA Seal, which supports its use for diabetic foot care considerations.